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Posté : mer. 24 févr. 2016 07:44
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,Rindo attained 12-15 months PFS improvement for patients, whereas anecdotal DCVax-L data and modeling show around 24 months PFS improvement (nearly double).This would reflect an OS of 36 months, which anecdotal data also supports.Also, should data indeed show such an improvement over SOC, the Ph III DCVax-L trial would be halted mid-2015, and a BLA filed.CLDX has to wait until at least early 2017 to learn Rindo's fate.Each of the trials included both newly diagnosed (early stage) GBM, and recurrent (late stage) GBM.7.9 for control.Data on some 276 patients would dwarf the open-label patient population with rGBM being treated with Rindo.
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,Most farmers are not expecting a significant increase in corn yields for 2013 and expect moisture levels to continue to be sub-optimal.Yields from additional acres in the Western Corn Belt, Reserve Programs, and the South will be well below the national average.Heavy rainfall in Argentina's Pampas region and hot dry weather in Brazil has delayed planting, which could lead to sub-optimal yields.I wrote this article myself, and it expresses my own opinions.I am not receiving compensation for it.Technical Picture: Medium Term Bullish, Short Term BearishWe look at the technical picture first for a number of reasons, including:Chart Don't Lie: Dramatic headlines and dominant news themes don't necessarily move markets.
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,Eventually the shark released him, and he was rushed to a hospital, where they were able to save his leg.Two days later, a great white was caught in Raritan Bay.As game developers gear up for the holiday season, shareholders must place a keen focus on the macro trends.While recent employment figures were better than expected, the unemployment rate still rose to 8.3% - well above what is necessary for a healthy economy.In such a climate, investors should be pickier about their consumer good picks.In my view, Microsoft (NASDAQ:MSFT) and Activision Blizzard (NASDAQ:ATVI) are undervalued while Electronic Arts (NASDAQ:EA) is overvalued.
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,I assumed ~$40mm of capex per year to maintain and operate the mines.Given they are estimating $300 million this year in overall capex and most of that is just maintenance capex, I thought this was a conservative estimate.If there was zero capex required for the next 5 years, the NPV would be $470 million to get a sense for how important this assumption is.Iron Ore business manages and operates five iron ore mines in Michigan and Minnesota with annual rated capacity of 32.9 million tons - representing 59% of total US pellet production capacity.Production is generally sold via long-term supply agreements with price adjustment provisions.
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,The yields were two and three percent.Now they're double digits.is immune to that.These are debt traps.You get into a situation where you can't borrow any more at these low interest rates.Once the interest rates start spiking, they'll lose control of the situation.It's a major game-changer.And so I think investors and speculators need to put this into their thinking, tattoo it on their foreheads: The potential exists for the United States government to completely lose control of these ultra-low interest rates.The low interest rates don't really do any good.They punish savers.Including stock awards, Housenbold was paid $16.2M in 2014, up from $13.2M the year prior (Source: company proxy statement).
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,Rindo attained 12-15 months PFS improvement for patients, whereas anecdotal DCVax-L data and modeling show around 24 months PFS improvement (nearly double).This would reflect an OS of 36 months, which anecdotal data also supports.Also, should data indeed show such an improvement over SOC, the Ph III DCVax-L trial would be halted mid-2015, and a BLA filed.CLDX has to wait until at least early 2017 to learn Rindo's fate.Each of the trials included both newly diagnosed (early stage) GBM, and recurrent (late stage) GBM.7.9 for control.Data on some 276 patients would dwarf the open-label patient population with rGBM being treated with Rindo.
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,Most farmers are not expecting a significant increase in corn yields for 2013 and expect moisture levels to continue to be sub-optimal.Yields from additional acres in the Western Corn Belt, Reserve Programs, and the South will be well below the national average.Heavy rainfall in Argentina's Pampas region and hot dry weather in Brazil has delayed planting, which could lead to sub-optimal yields.I wrote this article myself, and it expresses my own opinions.I am not receiving compensation for it.Technical Picture: Medium Term Bullish, Short Term BearishWe look at the technical picture first for a number of reasons, including:Chart Don't Lie: Dramatic headlines and dominant news themes don't necessarily move markets.
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,Eventually the shark released him, and he was rushed to a hospital, where they were able to save his leg.Two days later, a great white was caught in Raritan Bay.As game developers gear up for the holiday season, shareholders must place a keen focus on the macro trends.While recent employment figures were better than expected, the unemployment rate still rose to 8.3% - well above what is necessary for a healthy economy.In such a climate, investors should be pickier about their consumer good picks.In my view, Microsoft (NASDAQ:MSFT) and Activision Blizzard (NASDAQ:ATVI) are undervalued while Electronic Arts (NASDAQ:EA) is overvalued.
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,I assumed ~$40mm of capex per year to maintain and operate the mines.Given they are estimating $300 million this year in overall capex and most of that is just maintenance capex, I thought this was a conservative estimate.If there was zero capex required for the next 5 years, the NPV would be $470 million to get a sense for how important this assumption is.Iron Ore business manages and operates five iron ore mines in Michigan and Minnesota with annual rated capacity of 32.9 million tons - representing 59% of total US pellet production capacity.Production is generally sold via long-term supply agreements with price adjustment provisions.
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,The yields were two and three percent.Now they're double digits.is immune to that.These are debt traps.You get into a situation where you can't borrow any more at these low interest rates.Once the interest rates start spiking, they'll lose control of the situation.It's a major game-changer.And so I think investors and speculators need to put this into their thinking, tattoo it on their foreheads: The potential exists for the United States government to completely lose control of these ultra-low interest rates.The low interest rates don't really do any good.They punish savers.Including stock awards, Housenbold was paid $16.2M in 2014, up from $13.2M the year prior (Source: company proxy statement).
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