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,Cancer Res.2008 Jul 15;68(14):5955-64.12 Sloan AE, Dansey R, Zamorano L, Barger G, Hamm C, Diaz F, Baynes R, Wood G.Adoptive immunotherapy in patients with recurrent malignant glioma: preliminary results of using autologous whole-tumor vaccine plus granulocyte-macrophage colony-stimulating factor and adoptive transfer of anti-CD3-activated lymphocytes.Neurosurg Focus.2000 Dec 15;9(6):e9.13 Yamanaka R, Homma J, Yajima N, Tsuchiya N, Sano M, Kobayashi T, Yoshida S, Abe T, Narita M, Takahashi M, Tanaka R.Clinical evaluation of dendritic cell vaccination for patients with recurrent glioma: results of a clinical phase I/II trial.
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,But they are very brittle.If you where to drop it on something hard it would break.Fixed blades are your basic straight knives they do not fold and need to have a sheath to cover the blade and are normally worn on a belt.these knives are much stronger that there folding brothers due to the tang running down the handle.It also helps that there are no moving parts to the fixed blade knives.Folding knives or pocket knives have a pivot point that folds the blade into the handle.Most of these have some sort of locking system on them.Some of the most popular are the slip joint, lock back, liner lock, frame lock, button lock, axis lock.
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